By Ana Catarina Mamede, Maria Filomena Botelho
This ebook describes the human amniotic membrane from its starting place, characterization and clinical purposes, summarizing the entire most up-to-date advancements and findings on the topic of this tissue with contributions from many of the major researchers within the box. The e-book addresses matters for its maintenance, separation and id of amniotic membrane-derived cells, in addition to the aptitude moral matters inquisitive about their use. the subject of this ebook is especially pertinent for clinicians and researchers serious about the examine and use of this tissue.
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Extra info for Amniotic Membrane: Origin, Characterization and Medical Applications
Akle C, Adinolfi M, Welsh K et al (1981) Immunogenicity of human amniotic epithelial cells after transplantation into volunteers. Lancet 2:1003–1005 8. Cornwell KG, Landsman A, James KS (2009) Extracellular matrix biomaterials for soft tissue repair. Clin Podiatr Med Surg 26:507–523 9. Tseng SC, Li D-Q, Ma X (1999) Suppression of transforming growth factor-beta isoforms, TGF-beta receptor type II and myofibroblast differentiation in cultured human corneal and limbal fibroblasts by amniotic membrane matrix.
There are six different cell surface receptors or integrin receptors which recognize this site, but the conformation of the fibronectin is also important for the specificity and affinity of this cell-fibronectin recognition . Integrin receptors can mediate cell adhesion and migration on fibronectin and other extracellular molecules . Laminins are a major component of basement membranes and are formed of several subunits linked together by disulphide bonds, forming a cross-like structure.
Solomon A, Rosenblatt M, Monroy D et al (2001) Suppression of interleukin 1alpha and interleukin 1beta in human limbal epithelial cells cultured on the amniotic membrane stromal matrix. Br J Ophthalmol 85:444–449 2 Biochemical Properties of Amniotic Membrane 37 5. Kim JS, Kim JC, Na BK et al (2000) Amniotic membrane patching promotes healing and inhibits proteinase activity on wound healing following acute corneal alkali burn. Exp Eye Res 70:329–337 6. King A, Paltoo A, Kelly R et al (2007) Expression of natural antimicrobials by human placenta and fetal membranes.
Amniotic Membrane: Origin, Characterization and Medical Applications by Ana Catarina Mamede, Maria Filomena Botelho