By Ognyan Ivanov
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Extra resources for Applications and Experiences of Quality Control
Main treatment sites High dose rate machines may have clinical indications in the treatment of a variety of different organs either as a primary treatment or as a complementary therapy. As a result, there are a large number of applicators and accessories designed specifically to fit the geometrical needs of each treatment site. Among the numerous applications  for HD brachytherapy, the three main areas are: Prostate: Two techniques are in use: 1. Temporary implants using a stepping 192Ir HDR source to deliver large single-dose fractions has gained acceptance with current radiobiological models that predict a low [alpha]/[beta] ratio for prostate cancer, and 2.
Introduction Brachytherapy refers to the delivery of radiation directly into or onto the surface of the area to be treated. , the uterus, vagina, bronchus, esophagus, and rectum), can be placed on the surface of tumors in the skin or may be placed directly into a tissue by interstitial techniques such as those used in the head and neck region, prostate, and breast. One of the main objectives of brachytherapy is to ensure an accurate and safe dose delivery to a target volume while avoiding unnecessary delivery to surrounding healthy tissue.
For normally distributed data, with δ = gσ ( g > 0), the following sample weights are used: 1 Wt = ( Xt − µ0 )/σ − g/2 (13) 2 Wt = ( Xt − µ0 )/σ + g/2 34 Applications and Experiences of Quality Control and for dichotomous data: Wt1 = log p0Xt (1 − p0 )1− Xt ( p0 + δ ) X t (1 − p0 − δ )1 − X t (14) Given the fact that one may start monitoring with an LC-CUSUM test and then, once adequate performance has be shown, continue monitoring with a CUSUM test, confusion may arise in the definition of the adequate and inadequate performance levels under the null and alternative hypotheses for the CUSUM and LC-CUSUM tests.
Applications and Experiences of Quality Control by Ognyan Ivanov