Read e-book online Bacteriocins: Ecology and Evolution PDF

By Margaret A. Riley, Milind A. Chavan

ISBN-10: 3540366032

ISBN-13: 9783540366034

Microbes produce a rare array of safety structures. those comprise bacteriocins, a category of antimicrobial molecules with slim killing spectra, produced through micro organism. The e-book describes the variety and ecological function of bacteriocins of Gram-positive and Gram-negative micro organism, featuring a brand new class scheme for the previous and a state of the art examine the function of bacteriocins in bacterial conversation. It discusses the molecular evolution of colicins and colicin-like bacteriocins, and gives a latest evaluate of archaeocins, bacteriocin-like antimicrobials produced by means of archaebacteria. in addition, numerous modeling (in silico) reports elucidate the function of bacteriocins in microbial neighborhood dynamics and health, delving into rock-paper-scissors festival and the counter-intuitive survival of the weakest. The booklet makes compelling examining for a multi-faceted medical viewers, together with these operating within the fields of biodiversity and biotechnology, significantly within the human and animal well-being area.

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Extra info for Bacteriocins: Ecology and Evolution

Example text

Riley Ferrer S, Viejo MB, Guasch JF, Enfedaque J, Regue M (1996) Genetic evidence for an activator required for induction of colicin-like bacteriocin 28b production in Serratia marcescens by DNA-damaging agents. J Bacteriol 178:951–960 Fredericq P (1957) Colicins. Annu Rev Microbiol 11:7–22 Fredericq P (1963) On the nature of colicinogenic factors: a review. J Theor Biol 4:159–165 Gordon DM, Riley MA (1999) A theoretical and empirical investigation of the invasion dynamics of colicinogeny. Microbiology 145(3):655–661 Guasch JF, Enfedaque J, Ferrer S, Gargallo D, Regue M (1995) Bacteriocin 28b, a chromosomally encoded bacteriocin produced by most Serratia marcescens biotypes.

Much of the burgeoning interest in the bacteriocin-producing LAB is driven by their perceived potential practical applications either to food preservation or as probiotics. In this chapter, we propose that all of the currently confirmed bacteriocins of Gram-positive bacteria can be classified into four broad groups: (1) lantibiotics, (2) small non-modified peptides, (3) large proteins, and (4) cyclic peptides. 1 Bacteriocins: A Historical Perspective The term antibiotic is generically used to describe substances produced by organisms that selectively interfere with the growth of other organisms.

Killing activity across a genera does exist, one such example being 28B produced by Serratia marcescens which targets E. coli. The sequence of the translocation domain of 28B is remarkably similar to that of colicins A and U, which also kill E. coli. The translocation domains of S-type pyocins, colicins E2, E3 and cloacin DF13 are similar to each other. However, chimeric constructions of pyocin and colicin domains do not result in expected exploitation of the translocation system across the species.

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Bacteriocins: Ecology and Evolution by Margaret A. Riley, Milind A. Chavan


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